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Updated by tashanyanaidoo on Feb 26, 2025
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The Microbial Metalhead: Cupriavidas metallidurans Eats Toxic Metals for Breakfast

Cupriavidas metallidurans is a fascinating bacterium with the ability to thrive in toxic, metal-contaminated soils. Its bioremediation potential allows it to detoxify polluted environments by removing harmful metals.

Industrial activities, especially mining, severely impact the environment and pose a risk to human health. I chose to adopt this bacterium because studying such microbes can help combat pollution and restore ecological balance.

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1. Mining/Industrial Sites

1. Mining/Industrial Sites

Human activities contribute to pollution, with mining releasing toxic metals like cadmium, lead, mercury, and arsenic into soil and water. Acid mine drainage and waste cause heavy metal accumulation, threatening ecosystems and human health. Yet, some bacteria thrive in these conditions — Cupriavidus metallidurans is one such bacterium.

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2. Cupriavidus metallidurans

2. Cupriavidus metallidurans

The image above features my adopted bacterium, Cupriavidus metallidurans. Its taxonomic hierarchy is as follows:

Domain: Bacteria
Phylum: Pseudomonadota
Class: Betaproteobacteria
Order: Burkholderiales
Family: Burkholderiaceae
Genus: Cupriavidus
Species: Cupriavidus metallidurans

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3. Bacterial Characteristics

3. Bacterial Characteristics

Cupriavidus metallidurans is a motile, rod-shaped, Gram-negative facultative anaerobe found in metal-rich, polluted environments. Originally isolated from a zinc factory, it is a chemoautotroph that oxidizes heavy metals for energy, aiding in pollution cleanup.

(https://bacdive.dsmz.de/strain/2038, https://genome.jgi.doe.gov/portal/ralme/ralme.home.html)

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4. Ecological Role and Importance

4. Ecological Role and Importance

Cupriavidus metallidurans aids bioremediation by enzymatically transforming toxic metal ions into less harmful forms, reducing metal toxicity in contaminated environments. This supports ecosystem recovery, benefiting organisms like nitrogen-fixing bacteria that maintain soil health.

(https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0017555&type=printable, https://pmc.ncbi.nlm.nih.gov/articles/PMC7763483/pdf/microorganisms-08-01952.pdf)

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5. Application and benefits

5. Application and benefits

Beyond bioremediation, Cupriavidus metallidurans has promising applications in biomineralization, transforming dissolved metal ions into stable minerals. It has been used for gold biomineralization, converting soluble gold compounds into inert nanoparticles. This process has potential in nanotechnology, bioleaching, and metal recovery, providing eco-friendly metal extraction methods.

(, https://www.nature.com/articles/495S12a)

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6. Challenges and Conservation

6. Challenges and Conservation

Cupriavidus metallidurans, mainly known for bioremediation, has been linked to rare infections in immunocompromised individuals. Ethical concerns include biosafety, antibiotic resistance, and environmental risks. Proper containment is crucial to prevent ecosystem disruption or resistance gene transfer. While its benefits are significant, careful monitoring ensures safe application of this bacterium. (https://doi.org/10.1128/jcm.01947-10)

(https://doi.org/10.1128/jcm.01947-10)