Genizer LLC
Liposome extruders are mainly used for the liposome formulation and achieving uniform size distributions. It is an ideal instrument to generate nanoscale liposome formulations, and to prepare exosomes and artificial cell membranes. By utilizing the tracked-etched filter membranes, the liposome extruders are capable of capturing large particles, precipitation and achieving sterile filtration.
The HandExtruder is a manually powered extruder designed for the formulation of 0.25mL-2.0mL liposome and lipopolyplex with small samples. The sample is passed back through the membrane by being pushed back and forth between two syringes. Homogeneous samples can be produced quickly and easily in minutes; typically 5-10 passes are sufficient to produce a sample with uniform liposome size.
The Genizer Jacketed Liposome Extruder is compressed air-driven and temperature-controlled, from testing to manufacturing production of liposome and lipopolyplex, for drug and gene delivery.
Genizer Online Liposome Extruders can be connected with a sanitary pump or high pressure homogenizer and are temperature controlled, from testing to manufacturing production of liposomes and lipopolyplex, for drug and gene delivery.
This video introduces the genizer series of pneumatic liposome extruders.The Genizer Jacketed Liposome Extruders is compressed air-driven and temperature-con...
Learn more about the smallest liposome extruder in our product line, the HandExtruder! The HandExtruder works with manual power, meaning you can operate it u...
Liposome Extruders: Learning How it works, Types, Applications
Working Principles: A liposome is a spherical-shaped vesicle composed of phospholipid bilayers. Phospholipid bilayers are critical components of cell membranes, with hydrophilic and hydrophobic properties.
*Genizer *offers a comprehensive range of extruders suitable for researchers and manufacturers across all scales, from lab-scale HandExtruder and GJE-10mL/100mL models for small-scale research and development, to pilot-scale GJE-800mL/3000mL models for larger experiments and production runs, and the GOE-8L/25L extruder for large-scale commercial production. This means that regardless of the scale of the project, Genizer has an extruder that can meet the requirements.
