Studies have shown reductions within the reaction capability with the aging process (immunosenescence). Lifestyle factors (physical activity and diet) are investigated as potential adjuvants to enhance the impact of vaccines on the system within the older. Considering the results of the many studies , The apply of physical activity improves responses to to the influenza vaccine,so once transferring these findings to COVID-19 , the importance of standard physical activity within the specific older population becomes very relevant throughout the COVID-19 pandemic.