creativebiostructure
Creative Biostructure is a biotech company focused on accelerating drug discovery based on its expertise in structural biology and membrane protein.
Target structure information can be utilized in multiple links of drug discovery, such as target selection, identification and optimization of hits, development of final properties of compounds using multi-threaded processes, as well as reconstruction of biological macromolecular structures by rational design to optimize their drugability. Moreover, the high drug attrition rate associated with late-phase clinical trials in drug development is an important reason for the rising cost, which further promotes the demand for obtaining accurate target three-dimensional (3D) structure information to reduce the possibility of drug failure. Leveraging extensive expertise in structural biology and in silico drug design, Creative Biostructure provides comprehensive target 3D structure analysis solutions.
https://drug-discovery.creative-biostructure.com/target-3d-structure-analysis-p14
Lead discovery and optimization play a crucial role to determine the quality of clinical candidates. After this process, a set of compounds can be screened that interact with the target and the confirmed hits have specific activity against the target. Creative Biostructure performs comprehensive lead discovery and optimization solutions including library construction, library screening (in silico, in vitro and in vivo), hit-to-lead optimization and preclinical evaluation, etc.
https://drug-discovery.creative-biostructure.com/lead-discovery-and-optimization-p19
