Protein supplements are a large part of the health regiment of all endurance athletes. However, protein supplements are the most useful within a specific time frame. Supplements are used for all kind of different purposes and can be recommended** best time to take supplements** at different times of the day, based on varying needs. Many other supplements are suggested to help several symptoms related to disease or illness.Over-the-counter supplements are typically used to mitigate mineral and vitamin deficiencies. Vitamin B supplements are the most common. Taking mineral supplements on an empty stomach can produce undesired side effects, most notably and upset stomach. It may be suggested to take the with meals.