The pharmaceutical industry in the United States is rapidly expanding in order to accommodate the need for new pharmaceutical products approved by the FDA (Food and Drug Administration). In order to be approved by the FDA, the production facilities making these new products must be designed, built and commissioned to meet stringent criteria necessary to validate the process. As such, the quality of the parts and construction of pharmaceutical piping systems has become increasingly important. In 1997, ASME published the Bioprocessing Equipment Standard (ASME BPE) for design, materials, construction, inspection, and testing of equipment for use in the biopharmaceutical industry. Now, engineers and quality control professionals have a measurable guideline for specifying and purchasing equipment.