antibody mouse

Creative Biolabs now provides a wide range of high-quality premade phage display antibody libraries from human, mouse, rabbit, chicken, etc.

Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation.

This gene encodes a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. The encoded protein may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia. Multiple transcript variants encoding distinct isoforms have been identified for this gene, however, the full length nature of some variants has not been determined. [provided by RefSeq]

AQP1 is a small integral membrane protein with six bilayer spanning domains that functions as a water channel protein. This protein permits passive transport of water along an osmotic gradient. This gene is a possible candidate for disorders involving imb

This gene encodes a water channel protein located in the kidney collecting tubule. It belongs to the MIP/aquaporin family, some members of which are clustered together on chromosome 12q13. Mutations in this gene have been linked to autosomal dominant and recessive forms of nephrogenic diabetes insipidus. [provided by RefSeq, Oct 2008]

This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. This protein is the predominant aquaporin found in brain and has an important role in brain water homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2017]

Aquaporin 5 (AQP5) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions. AQP0, AQ

Aquaporin 8 (AQP8) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 8 mRNA is found in pancreas and colon but not other tissues. [provided by RefSeq]

The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract from the normal 9-34 repeats to the pathogenic 38-62 repeats causes spinal bulbar muscular atrophy (SBMA, also known as Kennedy's disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2017]

Creative Biolabs provides one-stop solution to develop specific sdAbs against post-translational modification (PTM) sites.

This product is an alpaca single domain antibody recognizes BFP conjugated to Abberior STAR 488.

Dengue virus (DENV, shown in Fig.1) can cause dengue fever. It is a mosquito-borne, single positive-stranded RNA virus of Flaviviridae. There are four serotypes, including DENV 1, DENV 2, DENV 3, and DENV 4. In recent decades, the outbreak of dengue has grown dramatically in the world. Nowadays, dengue is endemic in more than 100 countries. The America, South-East Asia and Western Pacific regions are the most seriously affected. One of them, Asia represents 70% of the global burden of dengue fever. It is estimated that as many as 390 million infections occur every year, and many dengue infections are increasingly understood to be asymptomatic or subclinical. As a leading virology antibody provider, Creative Biolabs offers a various series of virology antibody services, such as discovery, development, customized services to help our customers achieve their research goals.

Creative Biolabs offers various kinds of secondary antibodies for promoting your researches.

Creative Biolabs offers ADC development services using payload conjugation to the modified antibody carbohydrate moieties

Creative biolabs offers customized ADC products targeting ERBB2 ( also known as HER2).

ADCs Toxins, Herboxidiene is described as a microbial product with antitumor activity. Herboxidiene seems to serve as a novel splicing inhibitor that specifically impairs the SF3b function by binding to SAP155. Herboxidiene in house activity data obtained from our manufacturing partner: Cellular line A549 (lung cander) IC50: 0,036 ug/ml - IC50 82 uM; Cellular line H116 (colon cancer) IC50 0,01 ug/ml - IC50 22,7 uM; Cellular line PSN1 (pancreatic cancer) IC50 0,036 ug/ml - IC50 82 uM - Cellular line T98G (glioblastoma) IC50 1 ug/ml - IC50 20,5 mM

ADCs Toxins, Ilimaquinone is a cell permeable, antimicrobial, anti-inflammatory, antimitotic and cytotoxic compound.

ADCs Toxins, Saporin is a plant toxin belonging to the ribosome-inactivating protein (RIP) family, a class of toxic enzymes that is widely distributed among plant genera whose activity is classically identified as rRNA N-glycosylase DNA.