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#Gefitinib is a #cancer medicine that is used for certain non-small cell #lung cancer and other cancers. Gefitinib is an EGFR inhibitor, which interrupts signaling through the epidermal growth factor receptor (EGFR) in target cells. #Drugssquare Online pharmacy available Gefitinib 250mg tablets under different-different brands like #Geftinat by Natco, #Gefticip by Cipla and #Iressa by Astra Zeneca.

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What do you mean by Lung Cancer?

Lung cancer originates in the tissues of the lungs or the cells lining the airways (the bronchi). These cells begin as and look like lung cancer cells under the microscope, with the exception of changes that occur in the process of becoming cancerous. If lung cancer spreads to other regions of the body, the cells are still lung cancer cells.

INFORMATION ABOUT LUNG CANCER, INCLUDING WHAT YOU SHOULD KNOW AND WHAT YOU SHOULD DO IF YOU HAVE LUNG CANCER

WHAT CAUSES LUNG CANCER?

The exact cause of lung cancer is still being investigated. Certain risk factors have been shown to play a part in causing cells to become cancerous. Risk factors for lung cancer include smoking, exposure to air pollution, and genetics.

DOES SMOKING CAUSE LUNG CANCER?

The major cause of lung cancer in men and women is mainly due to cigarette smoking. In 1876, a machine was invented to make rolled-up cigarettes and thus provided cheap tobacco products to almost everyone. At that time, lung cancer was relatively rare. Smoking dramatically increased and so did lung cancers following this innovation. Currently about 90% of all lung cancers are related to smoking. Radon gas, pollution, toxins, and other factors contribute to the remaining 10%. Cigarettes and cigarette smoke contains over 70 cancer-causing chemicals (carcinogens). Some of the carcinogens found in cigarette smoke include:

  • Lead (a highly poisonous metal)
  • Arsenic (an insecticide)
  • Cadmium (a battery component)
  • Isoprene (used to make synthetic rubber)
  • Benzene (a gasoline additive)
  • Cigar smoke is particularly heavy on tobacco-specific nitrosamines (TSNAs), which are considered particularly cancerous.
  • Lung Cancer and Cilia
  • Cigarette smoke damages and can kill hair-like projections on airway cells termed cilia. The cilia normally sweep out toxins, carcinogens, viruses, and bacteria. When the cilia are damaged or destroyed by smoke, all of these items may accumulate in the lungs and may cause problems such as infections or lung cancer.

TYPES OF LUNG CANCER:
There are two primary types of lung cancer:

Non-small cell lung cancer is most common, being responsible for 80 to 85 percent of cancers. This is the type of lung cancer more commonly found in non-smokers, women, and young adults.

Small cell lung cancer is responsible for around 15 percent of lung cancers. These lung cancers tend to be aggressive and may not be found until they have already spread (especially to the brain). They usually respond fairly well to chemotherapy but have a poor prognosis.
**
WHERE IS LUNG CANCER MOST COMMON?**
Unfortunately, lung cancer is common throughout the world. Overall, the countries with the most lung cancer worldwide include Hungary, Serbia, and Korea. Looking at lung cancer in women, however, the highest incidence is found in Denmark, followed closely by Canada and then the United States.

SIGNS OF LUNG CANCER

About 25 percent of people who have lung cancer will show no symptoms before they're diagnosed. Their cancer often is diagnosed from a routine chest X-ray or from a CT scan done for other reasons. But most who are diagnosed with lung cancer do have signs and symptoms of the disease. Here are the more common ones.

  • A cough that doesn't go away and gets worse over time
  • Constant chest pain
  • Coughing up blood
  • Shortness of breath, wheezing, or hoarseness
  • Repeated problems with pneumonia or bronchitis
  • Swelling of the neck and face
  • Loss of appetite or weight loss
  • Fatigue ** WHEN SHOULD YOU CONTACT A DOCTOR?**

Make an appointment with your doctor if you have any persistent signs and symptoms that worry you. They will perform a physical exam and possibly other tests, as well as discuss the symptoms you’ve been having. These other tests may include blood tests, imaging tests, and a bone marrow exam.

10 TIPS FOR LUNG CANCER PREVENTION

1 Don't Smoke
2.Check Your Home for Radon
3 Be Careful and Aware at Work
4 Be Careful and Aware at Home
5 Avoid Secondhand Smoke
6 Exercise for Lung Cancer Prevention
7 Eat a Variety of Fruits and Vegetables
8 Enjoy a Cup of Green Tea
9 Limit Your Intake of Alcohol
10 Be Wary of Supplements

TESTS TO DIAGNOSE LUNG CANCER

If there's reason to think that you may have lung cancer, your doctor can order a number of tests to look for cancerous cells and to rule out other conditions. In order to diagnose lung cancer, your doctor may recommend:

Imaging tests. An X-ray image of your lungs may reveal an abnormal mass or nodule. A CT scan can reveal small lesions in your lungs that might not be detected on an X-ray.
Sputum cytology. If you have a cough and are producing sputum, looking at the sputum under the microscope can sometimes reveal the presence of lung cancer cells.
Tissue sample (biopsy). A sample of abnormal cells may be removed in a procedure called a biopsy.

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Arimidex Breast Cancer Drugs - Introduction

Women treated for very early signs of breast cancer live LONGER than those who never get the disease. Breast cancer is caused by the development of malignant cells in the breast. The malignant cells originate in the lining of the milk glands or ducts of the breast (ductal epithelium). Breast cancer is the most common cancer in women, but it can also appear in men. Arimidex Contains Anastrozole and belongs to a class of medications called Nonsteroidal aromatase inhibitors. Arimidex is extremely effective in adjuvant therapy as well as in treating metastatic breast cancer. Anastrozole is known for its efficiency of decreasing the amount of estrogens produced by the body. Moreover, it has been proven effective in the off-label reduction of estrogens in men thus, minimizing the chances of benign prostatic hyperplasia, gynecomastia and hypogonadism in them.

How Arimidex Works?

ARIMIDEX is used to treat breast cancer in women who no longer have their menstrual periods either naturally, due to their age or after surgery, radiotherapy or chemotherapy. Anastrozole is a non-steroidal aromatase inhibitor, which reduces the amount of oestrogen made by the body. In some types of breast cancer, oestrogen can help the cancer cells grow. By blocking oestrogen, ARIMIDEX may slow or stop the growth of cancer.

How do I take Arimidex?

The usual dose is one tablet taken once a day. You should try to take your tablet at the same time each day; this will help you to remember it.
The tablets should be swallowed whole with a glass of water. They can be taken either with or without food.
If you forget to take a dose, you should just take your next dose as usual when it is due. Don't take a double dose to make up for a missed dose.
Keep taking this medicine every day until your doctor tells you to stop. You may be asked to keep taking it for a few years, depending on what other treatments you have had for your cancer.

When you must not take it :

  • Pregnancy: Do not take ARIMIDEX if you are pregnant or intend to become pregnant. ARIMIDEX may affect your developing baby if you take it during pregnancy.
  • Breastfeed: Do not breastfeed while taking ARIMIDEX. Your baby can take in ARIMIDEX from breast milk if you are breastfeeding.
  • Allergy: Do not take ARIMIDEX if you have an allergy to: Anastrozole, the active ingredient of ARIMIDEX
  • Symptoms of an allergic reaction may include shortness of breath, wheezing or difficulty in breathing; swelling of the face, lips, tongue or any other parts of the body; rash, itching or hives on the skin.
  • Do not take ARIMIDEX if you are a man. Men are not normally treated with ARIMIDEX.
  • Do not give ARIMIDEX to a child. ARIMIDEX is not recommended for use in children.
  • Do not take ARIMIDEX after the use by (expiry) date printed on the pack. Do not take ARIMIDEX if the packaging is torn or shows signs of tampering. If it has expired or is damaged, return it to your pharmacist for disposal
  • Do not use it to treat any other complaints unless your doctor tells you to.
  • Do not give this medicine to anyone else.

Things to be careful of
Be careful driving or operating machinery until you know how ARIMIDEX affects you. Some patients may occasionally feel weak or sleepy.

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THE FACTS ABOUT PROSTATE CANCER

Only men have prostate. The prostate gland is usually the size and shape of the walnut, and grows with age. It sits under the bladder, around the urethra, which is the tube through which urine and ejaculation pass. Its main job is to help semen - the liquid that carries sperm. Prostate cancer occurs in some cells in the prostate more quickly than normal replication, leading to tumors. Prostate cancer usually grows slowly, starts, and may never cause any problems. But some men have more likely to spread prostate cancer. If left untreated, these prostate cancer cells may spread from the prostate and invade distant parts of the body, particularly the lymph nodes and bones, to produce secondary tumors in a process known as metastasis.

DETECTING PROSTATE CANCER

Prostate cancer occurs when abnormal cells within the prostate grow in an abandoned way. It is the most common cancer in men and the chances of developing this type of cancer increase with age. The symptoms don't usually appear until the cancer has grown large enough to put pressure on the urethra and can include:

  • feeling the frequent or sudden need to urinate
  • finding it difficult to urinate (for example, trouble starting or not being able to urinate when the feeling is there or poor urine flow)
  • discomfort when urinating
  • finding blood in urine or semen
  • pain in the lower back, upper thighs or hips

These symptoms should be examined by your doctor, but they don't mean you have prostate cancer. Many men's prostates get larger as they get older, not due cancer but to conditions known as 'benign prostatic hyperplasia' or prostate enlargement.

IF YOU’VE BEEN DIAGNOSED WITH PROSTATE CANCER, THEN USE ABIRATERONE FOR TREATING PROSTATE CANCER

WHAT IS ZYTIGA?

Zytiga is used to treat certain kinds of prostate cancer which has metastasized to other parts of the body and it is not responding to other treatments. It is given in combination with another medications.

CLASSIFICATION AND MODE OF ACTION

Zytiga contains Abiraterone acetate as the active drug which is a steroidal antiandrogen. It inhibits enzyme CYP17A1 which is expressed in the testicular, prostate tumor and adrenal tissues. By inhibiting this enzyme Zytiga hinders the production of androgen hormones and that reduces the weight, number and size of the cancer cells.

HOW TO TAKE ZYTIGA?

Zytiga is used in conjunction with another medication for prostate cancer therapy. Take Zytiga twice before or after a meal with a glass of water. Usual dose is one tablet a day. The pills should not be broken or smashed Do not make any changes regarding the dosage or your treatment scheme without your doctor advice. In case of overdose seek for emergency medical help. Patient blood pressure will be regularly monitored, and you your blood will be frequently analyzed.

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Temozolomide Use :

Temozolomide is a prescribed drug that is used for the treatment of specific brain cancers like -

Refractory cancer *: Refractory cancer is also known as resistant cancer. A cancer is said to be refractory when it does not respond to cancer treatment.
*
Anaplastic cancer
: Anaplastic thyroid carcinoma is an aggressive form of cancer of the thyroid gland. It is one of the fastest growing tumors in older people and is more common in women than in men.

Astrocytoma cancer: Astrocytomas, also known as astrocytic tumours , are a type of brain cancer that belong to a group of tumour called gliomas. This type of cancer usually starts in the cerebrum, the largest part of your brain, but can also show up in the cerebellum (the back of the brain). It’s more common in men than women and most often shows up after age 45. Common symptoms include headaches and seizures.

Who Can't get Temozolomide Capsule?

Risk of infection: Temozolomide can reduce the number of white blood cells in your blood. This will make you more likely to get an infection. When the number of white blood cells is low, it’s called neutropenia. The number of white blood cells usually increases steadily and returns to normal before your next treatment. You will have a blood test before having more chemotherapy. If your white blood cell numbers are still low, your doctor may delay your treatment for a short time.

Bruising and bleeding: Temozolomide can reduce the number of platelets in your blood. Platelets are cells that help the blood to clot. This includes nose bleeds, bleeding gums, blood spots or rashes on the skin.

Anaemia (low number of red blood cells): Temozolomide can reduce the number of red blood cells in your blood. These cells carry oxygen around the body. If the number of red blood cells is low, you may be tired and breathless.

Feeling sick:This may happen in the first few days after chemotherapy. Your doctor can prescribe effective anti-sickness drugs to prevent or reduce sickness or vomiting.

Constipation: Temozolomide may make you constipated and cause tummy pain. It will help to drink at least two litres of fluids (three and a half pints) every day. Try to eat more foods that contain fibre such as fruit, vegetables and wholemeal bread. Also try to take regular gentle exercise.

Loss of appetite: You may lose your appetite during your treatment. Try to eat small meals regularly. Don’t worry if you don’t eat much for a day or two. If your appetite doesn’t improve after a few days, let your doctor know.

Raised blood sugar levels: Temozolomide may raise the levels of sugar in your blood. Symptoms of raised blood sugar include feeling thirsty, needing to pass urine more often and feeling tired. If you have these symptoms, tell your doctor or Pharmacist.

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