Silica Gel Adsorbents are used in Chromatography process which is used based on the type of mixture need to be separated. They are silica gel, aluminum oxide, silica gel for thin layer, flash and column chromatography. It is required to choose the perfect adsorbent based on the mixture of components as well as the type of application. Chromatography adsorbents are commonly used in pharmaceutical and chemical industries where the products are manufactured by the combination of variety of compounds. In order to make the final pure compounds or products by removing the impurities and other contaminants, such type of adsorbent is used to obtain highly effective result for pharmaceutical and natural products.