Top 10 interviews of Oprah Winfrey

Oprah hosted a rare prime-time interview with the late singer/entertainer at his Neverland Ranch in California. It became the most watched interview ever and the fourth most watched event in American television history.The embattled Jackson made a rare appearance, during which he attempted to dispel many of the bizarre rumors surrounding him. In the process, he told Winfrey he suffered from the skin-pigment disorder known as vitiligo.

Tom Cruise vividly and emotionally expressed love for his now ex-wife Katie Holmes by jumping around the set and hopping onto a couch. He repeatedly professed his love for his then girlfriend by saying “I’m in love, I’m in love.” The interview was carried out in 2005, this was when Katie Holmes was 26, while Cruise being 42 posed an obvious age difference. The couple are now divorced.

Newly elected president Barack Obama and first the lady Michelle Obama appeared on Oprah in Chicago in 2011. It was a strange coincidence that Obama had just announced Osama bin Laden’s death to the nation just before the episode aired. He spoke about his multicultural upbringing, political plans and his upcoming priorities and shared more insights about his family.

The late singer candidly spoke about her abusing drugs with her ex-husband Bobby Brown. She also spoke about her toxic marriage to bobby brown and her musical comeback.

To kick off the fall 2004 season, Oprah gave her studio audience a present. A big present. The members of the audience were given ribbon-tied boxes and repeatedly told not to open them. Or to shake them. She said that only one of the boxes contained a key to the gift — a brand-new Pontiac G6. Then, the audience started opening the boxes. Everyone had a shiny silver key. Everyone. As her fans screamed and cried, Oprah walked from one end of the stage to the other, bellowing, “You get a car, you get a car. . .”

Stepanek suffered from a rare form of muscular dystrophy and died at the age of 13. He was a poet and speaker, penning six volumes of bestselling Heartsongs poetry books, and a collection of peace essays that also became a best seller. This little kid had a heart of gold, and his message inspired Winfrey and millions of others.

Oprah introduced the world to patricia, her half-sister who she herself only discovered in October 2010. Winfrey’s half-sister Patricia, had been given up for adoption in Milwaukee, Wis., by Winfrey’s mother, Vernita Lee, in 1963. “I was 9 years old at the time, living with my father in Nashville, Tenn.,” Winfrey said. “I had no idea my mother was even pregnant.”

Oprah helped James Frey sell 4 million books when she chose his memoir, “A Million Little Pieces,” for her book club. But later when she found out about the fabrication of the book she skewered him and his publisher by asking the him tough questions ,addressing the truths and lies of his controvertial book.

Phillips's memoir High on Arrival was released, after which she appeared on The Oprah Winfrey Show. She told Winfrey that she first tried cocaine when she was 11 years old, and that her father did drugs with her and injected her with cocaine. During the interview, Phillips read excerpts from her book. She said that at the age of 19, on the night before her first wedding, "I woke up that night from a blackout to find myself having sex with my own father." It started with a drug-fueled rape at age 19, moved into his offer to run away with her and then ended 10 years later with a pregnancy and abortion.

In one of Oprah’s most popular episodes, actress Susan Lucci was floored when Oprah reunited her with the eight actors who’ve played her TV husbands on “All My Children,” including David Canary, Walt Willey and Michael Nader, Dex Dexter of “Dynasty.” The audience, which included many soap fans, was in Lucci heaven.