WebMD Feature Archive You've seen the antiaging skin care claims, in newspapers, magazines, and even online: ominous photos of hypodermic needles posed along side innocuous, even innocent-looking jars of cream. The message: Topical cosmetic creams promises the same wrinkle-relaxing, age-defying results as some pricey wrinkle-filling injections like Restalyne and Juva Derm, or even Botox.