The Heavy Painful Menstrual Cycles is a hormonal change taking place in woman’s body. The hormones estrogen and progesterone play a key role in regulating menstrual cycle. Each month, these changes prepare woman’s uterus for possibility of pregnancy. An endometrium, a thin layer of lining inside uterus developed naturally by estrogen. This formation of an endometrium is an ideal environment for fertilization of eggs. When there are no fertilized eggs, the estrogen and progesterone levels drop down.